The Nathan S. Kline Institute for Psychiatric ResearchThe Nathan S. Kline Institute for Psychiatric Research (NKI) investigates the causes, treatment, prevention, and rehabilitation of severe and persistent mental illnesses. Founded in 1952, NKI has earned a reputation for landmark contributions in the areas of psychopharmacological treatments for schizophrenia and major mood disorders, dementia research, clinical trials methodology, therapeutic drug monitoring, and the application of computer technology to mental health services.